Impact of L-Carnitine infusion on Lipid induced Insulin resistance - Carnitine infusion and Insulin resistance

niversiteit Maastricht0 个研究点目标入组 21 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•* Healthy (as determined by responsible physician based on a medical questionnaire)
•* Age: 18-40 years
•* Normal BMI: 18-25 kg/m2
•* Stable dietary habits
•* No use of medication interfering with investigated study parameters (as determined by responsible physician)

•* Haemoglobin levels < 7.8 mmol/L
•* Uncontrolled hypertension
•* Use of anticoagulants
•* Engagement in exercise > 3 hours a week
•* Being vegetarian or vegan (because of altered whole body carnitine status)
•* Alcohol and/or drug abuse
•* Unstable body weight (weight gain or loss > 5kg in the last 3 months)
•* Significant food allergies/intolerances (seriously hampering study meals)
•* Participation in another biomedical study within 1 month before the first study visit, which would possibly hamper our study results
•* Medication use known to hamper subject*s safety during the study procedures
•* Medication use known to interfere with investigated study parameters
•* Subjects with contra-indications for MRI
•* Subjects who intend to donate blood during the intervention or subjects who have donated blood less than three months before the start of the study
•* Subjects who do not want to be informed about unexpected medical findings
•* Subjects who do not want that their treating physician is informed

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