Intensive Glucose Control Versus Conventional:Tendency Of Better Clinical Outcome In Open Heart Surgery
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 98
- 试验地点
- 2
- 主要终点
- Duration of intubation
研究概览
简要总结
The purpose of the study is to seek if there is difference to state glucose level in 80-120mg/dl or 200mg/dl in patients submitted to open heart surgery
详细描述
Hyperglycaemia in the intensive care unit and perioperative period has been accused to be one of the causes of worse clinical outcome. It is known that in open heart surgeries the glucose level must be set less than 200mg/dl, but new trials had set the glucose level lower than that: 140mg/dl in some studies and even lower (80-110mg/dl). Our trial had the intention to seek if there is difference setting glucose level in 2 different ones would modifies clinical outcome.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult more than 21 years old
- •open heart surgery with cardiopulmonary bypass
排除标准
- •renal dysfunction
- •reoperation
- •use of inotropic support
- •neurological dysfunction
- •chronic pulmonary obstructive disease
- •emergency or urgency
结局指标
主要结局
Duration of intubation
ICU length
Blood transfusion
Infection rate
Renal dysfunction
Neurological dysfunction
Hospital length
Mortality
次要结局
- Length of surgery
- Length of cardiopulmonary bypass
- Parsonnet
- Canadian Multicenter index
- Physical status
- EuroSCORE