Cardiovascular Risk Predictors in Patients With Psoriasis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- SCORE2-OP risk (Systematic COronary Risk Evaluation2- Older Person)
研究概览
简要总结
The investigators are planning to find the right modification of traditionally used risk scores (PASI, DLQI) in patients with psoriasis of different severity to guide the treatment that could potentially extend life, improve cardiovascular outcomes and quality of life in patients with psoriasis and cardiovascular risk factors in a prospective observational study. The traditionally excluded groups of older patients with diabetes mellitus, decreased kidney function and those with potentially worse prognosis are going to be included in the study. As it's known, the number of those patients is on the rise each year and require a close attention of multidisciplinary teams.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age over 18 years
- •Written informed consent of the patient to participate in the study
排除标准
- •Age under 18
- •Pregnancy, lactation
- •Very high cardiovascular risk
- •Life-threatening, independently influencing prognosis and disabling diseases,
- •Mental disorders that do not allow to give informed consent or answer questions adequately
- •Refuse of the patient to participate in the study
结局指标
主要结局
SCORE2-OP risk (Systematic COronary Risk Evaluation2- Older Person)
时间窗: 1 year
Increased cardiovascular risk over the follow-up period (from low to very high)
次要结局
- Overall mortality(1 year)
- Cardiovascular mortality(1 year)
- Progression of psoriasis (PASI)(1 year)
- Hospitalization due to cardiovascular reasons(1 year)
- Quality of life (DLQI score)(1 year)
研究者
Olga Mironova
Associate Professor
I.M. Sechenov First Moscow State Medical University