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临床试验/ISRCTN56133161
ISRCTN56133161进行中(未招募)Unknown

The synergistic effect of low-level laser and pilocarpine hydrochloride on saliva in patients with head and neck cancer who receive radiochemotherapy: Clinical randomized controlled study

Damascus University0 个研究点目标入组 24 人开始时间: 2023年8月21日最近更新:
适应症

试验速览

阶段
Unknown
状态
进行中(未招募)
入组人数
24

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • 1. The minimum radiation dose to which the patient is exposed is 50 Gy
  • 2. Radiation should be at least above the parotid gland and the submandibular gland on both sides
  • 3. The patients are 18 years old or over
  • 4. The patients did not undergo radiotherapy before
  • 5. The patients did not undergo chemotherapy for at least the past two months
  • 6. Karnofsky performance scale above 60

排除标准

  • 1. Sjogren's syndrome, diabetes and autoimmune diseases
  • 2. Clinically significant uncontrolled cardiac, renal, pulmonary, visual problems or other chronic diseases that could potentially interfere with the evaluation of the safety and efficacy of pilocarpine
  • 3. Tricyclic antidepressants, antihistamines with anticholinergic effects or Beta-blockers
  • 4. Pilocarpine for ophthalmic indications was also excluded from the study
  • 5. Tumor located in the parotid gland, submandibular gland, the blood or the floor of the mouth

研究者

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