The Patient as a Driver of Change: an Intervention Study to Reduce the Use and Impact of Potentially Inappropriate Medications Among Older Adults
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 发起方
- 入组人数
- 300
- 试验地点
- 2
- 主要终点
- Complete discontinuation of the targeted potentially inappropriate medication (e.g. benzodiazepines, oxybutynin)
研究概览
简要总结
An educational intervention targeting community-dwelling older adults will lead to a reduction in potentially inappropriate prescriptions (e.g. benzodiazepines, oxybutynin).
Cessation of potentially inappropriate medications (e.g. benzodiazepines, oxybutynin)will lead to improved cognitive outcomes in older adults.
详细描述
This study tests the effectiveness of a knowledge transfer tool for empowering patients to engage in collaborative discontinuation of potentially inappropriate medication with their pharmacist and/or physician
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •65 year old human adults
- •who fill a prescription for at least 5 medications
- •community dwelling
- •chronic use (3 months or longer) of at least one potentially inappropriate medication (e.g. benzodiazepine, oxybutynin)
排除标准
- •patients with severe mental illness, dementia and epilepsy
- •concomitant consumption of any other antipsychotic medication (including lithium, olanzapine, clozapine, quetiapine, risperidone, haloperidol etc.)
- •concomitant consumption of any antiepileptic (including carbamazepine, valproate, gabapentin, lamotrigine, topiramate, oxcarbazepine etc.)
- •concomitant consumption of a cholinesterase inhibitor or memantine
结局指标
主要结局
Complete discontinuation of the targeted potentially inappropriate medication (e.g. benzodiazepines, oxybutynin)
时间窗: 6 months post-intervention
次要结局
- Cognitive function(6-months post-intervention)
- Sleep efficiency(6-months)
- incontinence-related self-efficacy(6-months post-intervention)
- frequency of urinary incontinence episodes(6-months post-intervention)
研究者
Cara Tannenbaum
Dr.
Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal