Observing Platelet Activability in a Once daily vs. a More frequent Aspirin intake regimen - OPA- & OMA

VU university medical center0 个研究点开始时间: 2015年2月3日最近更新: 2015年3月2日

适应症

试验速览

暂无简介。

•Outpatients being treated for stable cardiovascular disease
•by the cardiology department.
•Stable cardiovascular disease defined as: coronary artery disease, peripheral vascular disease or previous myocardial infarction.
•Intake of 80 mg of acetylsalicylic acid once a day.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 10
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 75

•Active bleeding
•Diabetes mellitus
•Thrombocytopenia
•Thrombocytosis
•Thrombopathy (e.g. von Willebrand disease, Glanzmann’s thrombasthenia and Bernard–Soulier syndrome)
•Any ischemic event or revascularization procedure (percutaneous coronary intervention or coronary artery bypass grafting) within the last six months.
•Alcohol intake the day before blood sampling.
•Non-compliance to the protocol
•Baxter rolls (i.e. presorted medicine by a pharmacist)
•Recent use of antiplatelet drugs, anticoagulants or drugs that are known to alter platelet function, other than aspirin (e.g. NSAID’s, tirofiban, eptifibatide, abciximab, beta-lactam antibiotics, dextran, SSRI’s, clomipramine & amitriptyline, dipyridamole, verapamil, diltiazem , ginkgo biloba, ginseng, St John’s wort).

发起方

VU university medical center