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临床试验/TCTR20200715008
TCTR20200715008尚未招募未知

Continuous Infusion vs. Intermittent Bolus Hydrocortisone Administration in Children with Catecholamine-Dependent Septic Shock: A Randomized Controlled Trial

none0 个研究点目标入组 108 人开始时间: 2020年7月15日最近更新:
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适应症

试验速览

阶段
未知
状态
尚未招募
发起方
入组人数
108
研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
1 Months 至 18 Years（—）
性别
All

入选标准

  • •Children 1 month to 18 year of age admitted to PICU with catecholamine-dependent septic shock who are at risk for adrenal insufficiency as followings and received loading dose of hydrocortisone;
  • •Risk for adrenal insufficiency:
  • •- Physical signs e.g. purpura fulminans or diagnosed of Waterhouse-Friderichsen syndrome
  • •- History of hypothalamic-pituitary-adrenal axis abnormalities e.g. congenital adrenal hyperplasia, pituitary gland disease
  • •- History of corticosteroid use either long term (longer than 2 weeks within last 6 months) or short term (not longer than 2 weeks within last 4 month
  • •- History of etomidate use
  • •- History of antifungals use within last 7 days

排除标准

  • •Hypersensitivity of hydrocortisone
  • •Do-not-resuscitate patients
  • •Post cardiac arrest
  • •Patient receiving treatment with antifungals for systemic fungal infections at time of randomization

研究者

发起方
none

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