NL-OMON50138招募中不适用
Decline in renal concentration ability in lithium treated patients - Nephrogenic diabetes insipidus (NDI) in lithium treated patients
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 51
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •o included in the previous study
- •o men and women
- •o age >= 18 years
排除标准
- •general contra-indications for participation in a trial:
- •-inability to give informed consent
- •-pregnancy
- •-unstable psychiatric condition
- •alternative causes of (nephrogenic) diabetes insipidus:
- •- hypokalemia (plasma potassium < 3.5 mmol/l)
- •- severe hypercalcemia (albumin-corrected plasma calcium > 2.80 mmol/l)
- •- hyperglycemia (plasma glucose > 10.0 mmol/l)
- •- history of amyloidosis, Sjögren*s syndrome or Sickle cell anemia
- •- previous treatment with ifosfamide
- •- established primary polydipsia or central diabetes insipidus
- •contra-indications for dDAVP administration:
- •- inability to comply with water restriction
- •- renal insufficiency (GFR < 45 ml/min/1.73 m2)
- •- hyponatremia (plasma sodium < 130 mmol/l)
- •- instable angina pectoris
- •- decompensated cardial insufficiency
- •- concomitant treatment with desmopressin or democlocycline
研究者
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