Study on feasibility of Targeted epidural spinal stimulation to Improve MObility recovery in patients with sub-acute spinal cord injury - STIMO-2

École Polytechnique Fédérale de Lausanne0 个研究点目标入组 10 人开始时间: 待定最近更新: 2024年4月15日

适应症

试验速览

暂无简介。

•1. Patient enrolled in the EMSCI study
•2. Patient eligible following stratification based on URP model* (see Figure 3)
•3. Age 18 to 70 years old included
•4. Focal spinal cord injury due to trauma
•5. Patient with history of SCI within the past 6 months (sub-acute SCI)
•6. Level of lesion (confirmed by MRI):
•o vertebral lesion T11 or above, and the distance between the tip of the conus
•medullaris and the location of spinal cord damage must be at least 70 mm,
•allowing for electrode placement
•o and neurological lesion T11 or above, with conus function preserved
•7. Psychological condition compatible with study participation
•8. Able and willing to fulfil all study procedures

•1. Spinal cord lesion due to neurodegenerative disease, spondylitis, tumor, or
•presence of a spinal stenosis
•2. Severe or chronic medical disorder pre-existing SCI affecting rehabilitation
•3. Active implanted device such as a pacemaker, implantable cardiac
•defibrillator or indication that might lead to implantation of such device.
•4. Inability to follow study procedures, e.g. due to language problems,
•psychological disorders, dementia
•5. Hematological disorders with an increased risk of hemorrhagic event during
•surgical interventions
•6. Permanent artificial ventilation
•7. Congenital or acquired lower limb abnormalities (affection of joints and
•8. Known or suspected drug or alcohol abuse
•9. Life expectancy of less than 12 months
•10. Pregnant or breast feeding
•11. Participation in other interventional study

发起方