Effects of a Physical Activity Program With Partial Vascular Occlusion on Body Composition, Biomechanics and Walking Energy in Overweight Sedentary Subjects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- DEXA technology
研究概览
简要总结
This project should allow the investigators to observe the effects of low load training under partial vascular occlusion (BFR) in comparison with resistance training at low load without partial vascular occlusion in sedentary people overweight on parameters : decrease in fat mass; increase in muscle mass 79; muscle strength; decrease in the energy cost of walking; increase in preferred walking speed; improvement in walking pattern in patients overweight. Training under partial vascular occlusion should facilitate physical activity in overweight people as it can be just as effective as a "classic" type training with heavy loads. Thus, this device could allow people for who wear heavy loads can present an obstacle to physical activity to feel more involved in the physical activity programs offered in medical or sports centers.
详细描述
The main objective of this study is to observe the effects of low load training under vascular occlusion (BFR) compared with low load resistance training without vascular occlusion in overweight sedentary people on parameters such as: decrease in fat mass; lower blood sugar levels as well as lower blood triglycerides and cholesterol levels; increased muscle mass; muscle strength; the reduction of the energy cost of walking; increasing the preferred walking speed; improving the walking pattern in overweight patients.
3.2 Primary and secondary endpoints
The first hypothesis is that the BFR drive will be effective in improving walking economy (thus reducing the energy cost of walking) and increasing the preferred walking speed, by improving walking patterns.
The second hypothesis is that BFR training makes it possible to modify the body composition in a slight way and to promote the gain of muscle strength in overweight individuals who do not practice physical activity beforehand. In addition, blood tests will show a decrease in blood sugar, blood triglyceride levels and cholesterol.
3.3 Study design
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
盲法说明
BFR inflated 20 mmHg
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •IMC between 25 and 35
- •vaccin against Covid-19
排除标准
- •hypertension diabete
结局指标
主要结局
DEXA technology
时间窗: One week following the training intervention
Body composition assessment: relative lean and fat mass in all body segments
Evaluation of muscle strength from an isokinetic device
时间窗: One week following the training intervention
eccentric and concentric peak torque of the knee extensor muscles
Analysis of the biomechanics of walking on a treadmill instrumented with power platforms.
时间窗: One week following the training intervention
calculation of the mechanical work
Evaluation of the energy cost of walking
时间窗: One week following the training intervention
on a treadmill, by indirect calorimetry with gaz exchanges
Evaluation of the preferential speed of walking in an ecological situation
时间窗: One week following the training intervention
using of a treadmill with measurement of the ground reaction forces
次要结局
未报告次要终点
研究者
Gregoire Millet
Professor
University of Lausanne