imProving Respiratory Outbreak Mitigation Through Point-of-care Testing in Long Term Care (PROMPT-LTC): A Cluster Randomized Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 24
- 试验地点
- 4
- 主要终点
- Number of long-term care residents infected with COVID-19, Influenza, or respiratory syncytial virus (RSV)
研究概览
简要总结
Outbreaks of seasonal respiratory viruses can spread rapidly in long-term care homes. Timely results for diagnostic tests remains a challenge for respiratory viruses due to the logistics of using a reference laboratory with delays leading to missed opportunities to implement virus-specific control measures to interrupt transmission resulting in larger outbreaks. Use of a point-of-care testing platform is a potential solution that provides faster results, but it is uncertain whether this translates into benefits for long-term care residents. This trial aims to assess whether rapid test results for respiratory pathogens (Influenza, Coronavirus disease of 2019 (COVID-19) and Respiratory Syncytial Virus) can impact the number and size of respiratory virus outbreaks in long-term care homes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- Long-term care facility engaged with an Ontario Health Team overseen by Sunnybrook Health Science Centre, Michael Garron Hospital or Humber River Health
排除标准
- •No signed statement of agreement for study participation
- •Pre-existing use of a point-of-care testing platform
结局指标
主要结局
Number of long-term care residents infected with COVID-19, Influenza, or respiratory syncytial virus (RSV)
时间窗: 7 months
The number of long-term care residents who contract Influenza, COVID-19 or RSV separated into the number of residents infected after an introduction is identified and the size of an outbreak of each virus.
次要结局
- The number of outbreaks of Influenza, COVID-19 or RSV(7 months)
- The number of long-term care residents infected during an outbreak of Influenza, COVID-19 or RSV(28 days)
- Frequency of hospital transfers for long-term care residents infected with Influenza, COVID-19 or RSV(14 days)
- Number of deaths in long-term care residents infected with Influenza, COVID-19 or RSV(28 days)
- Duration of outbreaks in of Influenza, COVID-19 or RSV in long-term care facilities(60 days)
- Secondary attack rate of high-risk exposures to each long-term care resident with Influenza, COVID-19 or RSV infection(28 days)