Adequate duration of antibiotic treatment in community acquired pneumonia categorized by pneumonia severity index (PSI)

Fundació Clínic per la Recerca Biomèdica0 个研究点目标入组 424 人开始时间: 2018年4月9日最近更新: 2018年8月20日

适应症

试验速览

暂无简介。

•1) Hospitalized patients diagnosed with Community Acquired Pneumonia: appearance of a new radiological infiltrate plus the presence of at least two of the following signs or symptoms: fever (> 38 ºC), cough, expectoration, chest pain, dyspnea or tachypnea, and signs of occupation of the alveolar space.
•2) A PSI score class IV or V.
•3) Patients who have received adequate antibiotic treatment according to clinical guidelines from the first hour of emergency room admission.
•4) Patients who achieve clinical stability: temperature =37.2 ºC, heart rate =100 beats / min, respiratory rate =24 breaths / min, systolic blood pressure> 90 mmHg; oxygen saturation> 90%; or oxygen blood pressure> 60 mmHg (15) before the fourth day.
•5) Signature of informed consent.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 212
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 212

•1) Immunosuppression: Coinfection with HIV and presence of AIDS, neutropenic or have received immunosuppressive treatment for any cause. Patients with chronic use of corticosteroids (prednisone or its equivalent)> 10 mg / day for 14 days.
•2) Patients hospitalized in the previous 14 days.
•3) Suspected multi-resistant germs of any cause.
•4) Hypersensitivity or alterations in the tendons associated with the fuoroquinolones.
•5) Pregnancy or lactation

发起方

Fundació Clínic per la Recerca Biomèdica