CTRI/2018/03/012482尚未招募Unknown
Evaluation of pretreatment with Lignocaine,Dexmedetomidine or Ketamine in providing relieffrom Propofol injection pain and withdrawalmovements during induction of Anaesthesia
Vardhaman Mahavir Medical College and Safdarjung Hospital1 个研究点 分布在 1 个国家目标入组 135 人开始时间: 2018年3月15日最近更新:
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 入组人数
- 135
- 试验地点
- 1
- 主要终点
- during induction of anaesthesia, using lignocaine, dexmedetomidine or ketamine as
研究概览
简要总结
1.To study the degree of alleviation of pain and withdrawal movements, with propofol injection during induction of anaesthesia, using lignocaine, dexmedetomidine or ketamine as pretreatment.
2.To study the variations in haemodynamic parameters.
HYPOTHESIS : Pretreatment with dexmedetomidine would be comparable to ketamine and lignocaine in providing relief from pain and withdrawal movements associated with propofol injection during induction of anaesthesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA grade I & II
- •BMI less than or equal to 30 kg/m2
- •undergoing elective surgical procedures under general anaesthesia with endotracheal intubation.
排除标准
- •History of pulmonary, renal, hepatic, endocrine, neurological or cardiovascular disease(including hypertension, those on beta blockers or digitalis),patients on any sedatives, anxiolytics or analgesics, history of drug abuse and psychiatric illness, known hypersensitivity to the study drugs.
- •Pregnant and nursing females and emergency surgical procedures.
- •Subjects with anticipated difficulty in venous access.
结局指标
主要结局
during induction of anaesthesia, using lignocaine, dexmedetomidine or ketamine as
时间窗: At the time of induction.
To study the degree of alleviation of pain and withdrawal movements, with propofol injection
时间窗: At the time of induction.
pretreatment.
时间窗: At the time of induction.
次要结局
- To study the variations in haemodynamic parameters.(At the time of induction, preintubation , intubation and post intubation.)
研究者
研究点 (1)
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