A Comparison Between Two Methods for Estimating the Extent of Perioperative Atelectasis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Atelectasis area
研究概览
简要总结
This study will compare an oxygenation test based on arterial blood gas analysis with computed tomography for estimating the extent of atelectasis.
详细描述
Computed tomography of the lungs is the gold standard for investigating the extent of atelectasis, which is common in the perioperative setting. Atelectasis increase the risk of postoperative pulmonary complications and result in pulmonary shunt, which is one of the two major causes of impaired oxygenation. The other cause is admixture of venous blood from poorly ventilated regions of the lungs. The investigators have developed an oxygenation test utilizing arterial blood gas analysis at different inspired fractions of oxygen, which may be used to distinguish between these two causes. This observational study aims to establish the agreement between computed tomography and the oxygenation test for estimating the extent of atelectasis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiology (ASA) class I-II.
- •Non-abdominal day case surgery under general anesthesia.
- •Patients enrolled in study registered in ClinicalTrials with NCT ID.
排除标准
- •Arterial oxygen saturation (SpO2) <90 % with 40% Venturi mask.
- •Unstable postoperative condition needing immediate treatment.
结局指标
主要结局
Atelectasis area
时间窗: 30 min after emergence from anesthesia
Atelectasis area as studied by computed tomography
次要结局
- Pulmonary shunt estimated by a standardised oxygenation test(30 min after emergence from anesthesia)
研究者
Lennart Edmark
Principal Investigator
Region Västmanland