Comparative Analgesic Effect Between Continuous Wound Infusion and Transverse Abdominal Plan Block for Abdominoplasty Surgery
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Pain score expressed on a visual analogue scale
研究概览
简要总结
The purpose of this randomized controlled study is to compare the postoperative analgesic effect of a continuous wound infusion of local anesthetics and a sole transverse abdominal plan (TAP) regional block in the surgery of Abdominoplasty Combined With Flank Liposuction. Local anesthetics products used are ropivacaine combined with clonidine. Similar amount of local anesthetics and clonidine are used.
详细描述
In a first group, patients receive, after induction of anaesthesia and before surgery, a TAP block (transverse abdominal plan block) with 3mg/kg Ropivacaine 0.5% (maximum 200 mg) and 150 microg Clonidine.
In a second group, before skin closure, a multiholes catheter was inserted beyond the skin. 20 mg Ropivacaine 0.2% added with 150 microg Clonidine was injected as bolus dose through this catheter followed by a continuous infusion of Ropivacaine 0.2% 10ml per hour during the following 9 hours (total dose of 200 mgr).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled for abdominoplasty combined with flank liposuction
排除标准
- •Allergy to local anesthetics or clonidine
- •Coagulation disorders
- •History of chronic pain
- •Alcohol or drugs dependance
- •Refusal of the patients
结局指标
主要结局
Pain score expressed on a visual analogue scale
时间窗: at 0,2,4,6, 8 hours, and day 1 and day 2 postoperatively
次要结局
- Piritramide consumption on Patient Controlled Analgesia (PCA) device(at 0,2,4,6, 8 hours, and day 1 and day 2 postoperatively)
- Scale of nausea(at 0,2,4,6, 8 hours, and day 1 and day 2 postoperatively)
- Scale of sedation(at 0,2,4,6, 8 hours, and day 1 and day 2 postoperatively)
- Scale of patient's satisfaction(at day 2 postoperatively)
- Number of patients with adverse events(daily during 48 hours postoperatively)