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临床试验/NCT03157934
NCT03157934招募中不适用

Schlaganfallkonsortium Rhein-Neckar (Stroke Consortium Rhine-Neckar)

University Hospital Heidelberg1 个研究点 分布在 1 个国家目标入组 12,000 人开始时间: 2017年10月26日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
12,000
试验地点
1
主要终点
Functional outcome

研究概览

简要总结

FAST is an investigator-initiated multicenter study embedded in a German multistate acute stroke network. The main objectives of the FAST study are to improve outcomes and quality of care for stroke patients, to quantify the number of patients in need of thrombectomy within an integrated stroke network, to study the best way of delivering and performing thrombectomy and to investigate the best model of pre-hospital selection and referral for stroke patients.

详细描述

Since 2015, mechanical thrombectomy in patients with large vessel occlusion has become an evidence based highly efficient treatment. In contrast to thrombolysis, thrombectomy can only be delivered by qualified interventionalists at comprehensive stroke centers. Thus, the implementation of thrombectomy into clinical practice remains a challenge. The investigators aim to establish a population based approach within a patient registry in a federal state overarching regional stroke network covering over 4 million inhabitants and integrating approximately 30 hospitals with different levels of expertise. The registry will include data from all acute ischemic stroke patients - approx. 12.000 patients p.a - within the network. The investigators plan to establish a central multi-interface platform integrating clinical data from the prehospital, intrahospital and rehabilitation phase including mandatory quality assurance, neurological and neuroradiological treatment and outcome data. The registry will allow addressing important questions, such as how many patients are candidates for thrombectomy, how many resources are needed to meet that demand and how treatment procedures and times can be improved. The overarching aim is to deliver high quality stroke care to every patient in the region.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 18 years or older
  • Patients with ischemic stroke who are admitted to one of the hospitals of the Stroke Consortium Rhein-Neckar (FAST)
  • informed consent

排除标准

  • no informed consent

结局指标

主要结局

Functional outcome

时间窗: 3 months after intervention

Functional outcome according to the modified Rankin Scale (mRS)

次要结局

  • Referral rates(Stroke onset to discharge from acute hospital; through study completion, an average of 2 years)
  • Number of patients receiving acute recanalisation therapies of all referrals(24 h after stroke onset)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Prof. Dr. Wolfgang Wick

Chairman of the Neurologic Clinic

University Hospital Heidelberg

研究点 (1)

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