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临床试验/NCT06307730
NCT06307730已完成不适用

Duration of Antibiotic Treatment for Infectious Pneumonia in Eldery Subjects

Centre Hospitalier de Saint-Denis1 个研究点 分布在 1 个国家目标入组 35 人开始时间: 2023年1月2日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
35
试验地点
1
主要终点
Weight

研究概览

简要总结

Pneumopathy is the leading cause of death from infectious disease in the elderly. Prior to 2021, the recommended duration of antibiotic therapy for pneumonia, in adults, was 7 days.

Two theses have shown that these recommendations were poorly applied in geriatric services. Indeed, the duration of treatment exceeded 7 days, and less than 30% of antibiotic antibiotic treatments were re-evaluated at 72 hours.

In 2021, the SPLIF ( published new recommendations reducing this duration to 5 days in the event of clinical improvement observed on the 3rd day of treatment. These new recommendations are based on studies, in which the average age of participants was 65 years. However, the average age of patients in geriatric short-stay departments is 84.7 years.

In addition, the geriatric population is characterized by immunosenescence, pulmonary vulnerability and undernutrition, raising questions about the validity of these recommendations in the geriatric population.

The investigators offer a monocentric, retrospective, observational study of the geriatric hospital Casanova to assess the application of SPLIF recommendations in the geriatric population.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All patient treated for bacterial/community/nosocomial pneumonia who stayed in the geriatric short-stay at Casanova's Hospital between January 2, 2023 and April 30, 2023

排除标准

  • HIV Positif
  • Immunosupressed patient
  • Complicated pneumonia (abcess, pleuropneumonia)

结局指标

主要结局

Weight

时间窗: Day 1

Phone Number

时间窗: Day 1

Sex

时间窗: Day 1

Age

时间窗: Day 1

Origins

时间窗: Day 1

Coming from Home, An institution...

Autonomy in daily life's score before hospitalisation

时间窗: Day 1

score between 0 (autonomous) and 6 (dependent)

Charlson's morbidity score

时间窗: Day 1

次要结局

未报告次要终点

研究者

发起方
Centre Hospitalier de Saint-Denis
申办方类型
Other
责任方
Sponsor

研究点 (1)

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