A Prospective Evaluation of Topography-guided LASIK Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Epithelial thickness maps
研究概览
简要总结
The investigators are analyzing outcomes of topography-guided LASIK surgery in participants with myopia and myopic astigmatism
详细描述
The investigators are analyzing outcomes of topography-guided LASIK surgery in participants with myopia and myopic astigmatism. The investigators will be monitoring changes in anterior segment optical coherence tomography epithelial thickness maps. The investigators will compare preoperative maps to postoperative maps at one, three, six and twelve months. In addition, the investigators will measure changes in epithelial maps from postoperative month through twelve months to help understand what is happening to the corneal epithelium to try to explain why UDVA and CDVA improves over time
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
盲法说明
N0ne
入排标准
- 年龄范围
- 18 Years 至 59 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Subjects age 18 and older with healthy eyes. Nearsightedness between -0.50 diopters and -8.00 diopters.
- •Subjects with up to 3.00 diopters of astigmatism.
- •Subjects with a spherical equivalent of up to -9.00 diopters.
排除标准
- •Subjects under the age of
- •Subjects with excessively thin corneas.
- •Subjects with topographic evidence of keratoconus.
- •Subjects with ectatic eye disorders.
- •Subjects with autoimmune diseases.
- •Subjects who are pregnant or nursing.
- •Subjects with more than 3.00 diopters of astigmatism
研究组 & 干预措施
Topography guided LASI
干预措施: Topography-guided LASIK (Procedure)
结局指标
主要结局
Epithelial thickness maps
时间窗: 12 months
Changes in anterior segment optical coherence tomography epithelial thickness maps.
次要结局
- Contrast visual acuity(12 months)
- Change in refraction over time(12 months)
- Predictability(12 months)
- Changes in corrected visual acuity(12 months)
- Uncorrected distance visual acuity(12 months)
- Quality of Vision(12 months)
- Residual astigmatism levels after surgery(12 months)
研究者
Edward E. Manche
Professor of Ophthalmology
Stanford University