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临床试验/NCT07157085
NCT07157085已完成不适用

AI-Driven Multitask Model for Guiding Treatment Decision-Making in Hepatocellular Carcinoma

Sun Yat-sen University0 个研究点目标入组 7,000 人开始时间: 2008年1月1日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
7,000
主要终点
Overall Survival

研究概览

简要总结

We will integrate multi-modal cardiac data via an AI multitask framework to develop and validate concurrent models for liver function, treatment prognosis, and microvascular invasion (MVI) prediction in hepatocellular carcinoma. The resulting tool will be prospectively deployed to guide personalized surgical, TACE, and systemic therapy decisions.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age 18-75 years;
  • HCC diagnosed according to the European Association for the Study of the Liver/American Association for the Study of Liver Diseases criteria)
  • Eastern Cooperative Oncology Group performance status < 2;
  • Child-Pugh class A or B liver function;

排除标准

  • HCC combined with other malignancies;
  • missing image data during perioperative period;
  • lost to follow-up > 12 months.

结局指标

主要结局

Overall Survival

时间窗: 60 months

from diagnosis of HCC to death or last follow-up

次要结局

  • Progression-free survival(60 months)

研究者

发起方
Sun Yat-sen University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Zhen-Wei Peng

Professor

Sun Yat-sen University

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