EUCTR2007-003921-25-SE进行中(未招募)不适用
The effect of selective PDE-5 inhibition on capillary recruitment, glucose uptake and endothelial function following a mixed meal in patients with type 2 diabetes
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中(未招募)
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •To be acceptable for the study the type 2 diabetic subjects have to fulfill the following criteria: 1) Post-menopausal state, defined as natural amenorrhea for at least 12 months, age 52-67 yr or males 40-65 years; 2) Type 2 diabetes diagnosed or indicated by fasting or 2-hr OGTT plasma glucose levels (diabetes duration < 3 years).
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •1) Subjects with concurrent use of nitrates or NO donors, history of coronary heart or cerebrovascular disease, cardiac failure (stages NYHA II-IV), uncontrolled hypertension, significant diabetic complications, and inadequate glycemic control (HbA1c > 6.5%, ref values: 3.5-5.3%) will be excluded; 2) Patients on glitazones, insulin, beta-blockers, ACE-inhibitors, Angiotensin II Receptor subtype 1 Blocker or corticosteroids will be excluded.
研究者
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