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临床试验/NCT05491798
NCT05491798招募中不适用

A Big Data-based Cohort Study for Cataract Patients

Sun Yat-sen University1 个研究点 分布在 1 个国家目标入组 1,000 人开始时间: 2020年7月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
1,000
试验地点
1
主要终点
Change of best corrected visual acuity

研究概览

简要总结

Cataract is an important cause of blindness and visual impairment worldwide. At present, the only effective treatment method is surgery. The visual function of most patients can be significantly improved after surgery, but there are still 5-20% of patients whose visual function cannot be improved after surgery. Previous studies have found that the surgical complications and postoperative visual function of cataract patients are closely related to the condition of the fundus, but the current fundus camera cannot perform clear fundus imaging of cataract patients, and the existing potential visual inspections, such as retinal visual inspection, are also inaccurate. Predict postoperative visual acuity. Therefore, there is an urgent need for a reliable postoperative effect prediction system for cataract patients to provide reference for both ophthalmologists and patients.

This study intends to collect patient medical record information and traditional/ultra-wide fundus photos and other multi-modal data. Firstly, this study will use artificial intelligence technology to enhance fundus photos of cataract patients to obtain clearer fundus photos. Then this study will use both medical record information and traditional/ultra-wide fundus photographs to predict postoperative vision and visual function of cataract patients.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Candidates for cataract surgery (phacoemulsification and intraocular lens implantation) within a week.

排除标准

  • Unwilling or unable to receive fundus photography

结局指标

主要结局

Change of best corrected visual acuity

时间窗: Baseline and 1 week after surgery

Change of best corrected visual acuity from baseline to 1 week after surgery

Accuracy for detection of retinal disorders

时间窗: 1 week after surgery

Accuracy for detection of retinal disorders using enhanced fundus images

次要结局

未报告次要终点

研究者

发起方
Sun Yat-sen University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Haotian Lin

Clinical Professor

Sun Yat-sen University

研究点 (1)

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