A Big Data-based Cohort Study for Cataract Patients
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Change of best corrected visual acuity
研究概览
简要总结
Cataract is an important cause of blindness and visual impairment worldwide. At present, the only effective treatment method is surgery. The visual function of most patients can be significantly improved after surgery, but there are still 5-20% of patients whose visual function cannot be improved after surgery. Previous studies have found that the surgical complications and postoperative visual function of cataract patients are closely related to the condition of the fundus, but the current fundus camera cannot perform clear fundus imaging of cataract patients, and the existing potential visual inspections, such as retinal visual inspection, are also inaccurate. Predict postoperative visual acuity. Therefore, there is an urgent need for a reliable postoperative effect prediction system for cataract patients to provide reference for both ophthalmologists and patients.
This study intends to collect patient medical record information and traditional/ultra-wide fundus photos and other multi-modal data. Firstly, this study will use artificial intelligence technology to enhance fundus photos of cataract patients to obtain clearer fundus photos. Then this study will use both medical record information and traditional/ultra-wide fundus photographs to predict postoperative vision and visual function of cataract patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Candidates for cataract surgery (phacoemulsification and intraocular lens implantation) within a week.
排除标准
- •Unwilling or unable to receive fundus photography
结局指标
主要结局
Change of best corrected visual acuity
时间窗: Baseline and 1 week after surgery
Change of best corrected visual acuity from baseline to 1 week after surgery
Accuracy for detection of retinal disorders
时间窗: 1 week after surgery
Accuracy for detection of retinal disorders using enhanced fundus images
次要结局
未报告次要终点
研究者
Haotian Lin
Clinical Professor
Sun Yat-sen University
