NCT05873673进行中（未招募）2 期
The Effect of Coenzyme Q10 on Bone Regeneration in Jaw Defect After Cyst Enculation: A Randomized Controlled Clinical Trial
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 进行中（未招募）
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- bone density
研究概览
简要总结
10 patients in each group will undergo cyst removal under local anesthesia. After cyst removal, the cystic cavity will be filled with placebo gel in the control group or coenzyme gel in the coenzyme group.
Bone density and volume will be assessed by cone beam CT immediately postoperative and 6months later for all patients
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients with critical-size jaw cysts
- •Medically stable
- •No cystic lesion recurrence
排除标准
- •Cystic lesion recurrence
- •Medical problem
研究组 & 干预措施
coenzyme group
Active Comparator
干预措施: Coenzyme Q10 (Drug)
control group
Placebo Comparator
干预措施: control group (Drug)
结局指标
主要结局
bone density
时间窗: 6 months
measure the bone density of new bone in the cystic cavity at 6 months by cone beam CT
次要结局
- bone volume(6months)
研究者
Shaimaa Mohsen
lecturer of oral and maxillofacial surgery
Fayoum University
研究点 (1)
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