NCT00322114Unknown不适用
Mechanism of Prostate Cancer Prevention by Lycopene
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- Measurement of changes in percent free and total serum prostate-specific antigen (PSA) induced by lycopene
研究概览
简要总结
RATIONALE: Chemoprevention is the use of certain drugs or substances to keep cancer from forming, growing, or coming back. The use of lycopene, a substance found in tomatoes, may keep prostate cancer from forming.
PURPOSE: This randomized clinical trial is studying how well lycopene works in preventing prostate cancer in healthy participants.
详细描述
OBJECTIVES:
Primary
- Determine whether lycopene supplementation affects percent free and bound prostate-specific antigen (PSA) in healthy participants.
Secondary
- Determine whether lycopene reduces oxidative stress in these participants, as indicated by lipid peroxidation assay.
- Determine whether a 21-day washout period is sufficient to return lycopene, PSA, and lipid peroxidation products to baseline.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 主要目的
- Prevention
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Measurement of changes in percent free and total serum prostate-specific antigen (PSA) induced by lycopene
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Lycopene in Treating Patients With Prostate Cancer or Benign Prostatic HyperplasiaNonmalignant NeoplasmProstate CancerNCT00416390University of Illinois at Chicago120
已完成
1 期
Lycopene In Preventing of Prostate CancerProstate CancerNCT00006078University of Illinois at Chicago
已完成
1 期
Lycopene in Preventing Prostate Cancer in Patients Who Are at High Risk of Developing Prostate CancerProstate CancerNCT00416325University of Illinois at Chicago18
已完成
3 期
S9917, Selenium in Preventing Cancer in Patients With Neoplasia of the ProstatePrecancerous/Nonmalignant ConditionProstate CancerNCT00030901SWOG Cancer Research Network619
招募中
3 期
Effect of Lycopene on prostate cancer among native African patients : an open label Randomised clinical trial in KCMC and Ocean road cancer institute ,TanzaniaCancerPACTR202405488763956BLANDINA MMBAGA400