NCT03762551已完成不适用
Expression of Janus Kinase 1 in Vitiligo and Psoriasis Before and After Narrow Band UVB: a Case-Control Study
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 主要终点
- Measurement of the tissue level of JAK1 in both vitiligo and psoriasis patients before and after treatment with NB-UVB
研究概览
简要总结
Assessment of the level of JAK1 in both vitiligo and psoriasis patients before and after treatment with NB-UVB which is considered a gold standard therapy for both diseases.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 12 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age above 12 years of age.
- •psoriasis vulgaris or non-segmental vitiligo
- •patients who received no systemic or topical treatment at least 6 weeks prior to enrollment into the study.
排除标准
- •psoriasis patients with erythrodermic psoriasis, pustular psoriasis or associated psoriatic arthritis
- •vitiligo patients with segmental or universal vitiligo were excluded from the study.
- •any patient with a photosensitive disorder or any contraindication to phototherapy exposure, e.g., history or presence of malignant or premalignant skin lesions.
研究组 & 干预措施
vitiligo
Experimental
assess the level of JAK1 in vitiligo patients before and after treatment with NB-UVB
干预措施: skin biopsy (Other)
psoriasis
Active Comparator
assess the level of JAK1 in psoriasis patients before and after treatment with NB-UVB
干预措施: skin biopsy (Other)
controls
Other
assess the level of JAK1 in controls
干预措施: skin biopsy (Other)
结局指标
主要结局
Measurement of the tissue level of JAK1 in both vitiligo and psoriasis patients before and after treatment with NB-UVB
时间窗: 1 year
次要结局
未报告次要终点
研究者
Maha Fathy Elmasry
principal investigator
Cairo University
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