Antibacterial efficacy of zinc oxide nanoparticle coated elastomeric modules- A Randomized Clinical trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- To evaluate
研究概览
简要总结
Certain studies have evaluated the antibacterial efficacy of nanoparticle coated brackets and nanoparticle incorporated composite separately and studies have only evaluated the short term efficacy of nanoparticles on the cariogenic bacterial in the plaque. No studies have compared the efficacy of nanoparticle coated elastomeric modules over the uncoated modules. Long term studies are required to evaluate whether the efficacy of nanoparticles extends to reduced incidence of white spot lesions. Therefore, this study was designed to compare the efficacy of noanoparticles coated on elastomeric modules on long term against streptococcus mutans concentration in plaque and on the incidence of white spot lesions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- None
入排标准
- 年龄范围
- 15.00 Year(s) 至 30.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients undergoing orthodontic treatment Non- extraction fixed appliance cases Patients with good OHI.
- •Patients not taking medication Patients with no relevant medical history.
- •Patients with permanent dentition with full complement of teeth Patients with good gingival and periodontal health.
排除标准
- •Patients with poor oral hygiene Patients with extensive dental caries Patients with no history of illness or allergies.
- •Patients with periodontitis and bone loss.
结局指标
主要结局
To evaluate
时间窗: End of 3 months and end of one year
streptococcus mutans concentration in plaque
时间窗: End of 3 months and end of one year
using real-time
时间窗: End of 3 months and end of one year
polymerase chain reaction (PCR) and white spot lesion formation
时间窗: End of 3 months and end of one year
次要结局
未报告次要终点
研究者
DrHemashree J
Sri Ramachandra Institute of Higher Education and Research