ThoRAciC Trauma IntubatiON Risk Score for Blunt Trauma
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- needing for oro-tracheal intubation within day 7th from admission
研究概览
简要总结
The primary objective of this study is the evaluation of risk factors associated with orotracheal intubation in blunt chest trauma patients not intubated on the field and not fulfilling the criteria for intubation based on the Glasgow Coma scale score with the building of a predictive score based on those findings taking into account the clinical, laboratory and radiologic tests performed within 6 hours from hospital admission.
详细描述
Multicentre, prospective, observational study. All the consecutive blunt thoracic trauma patients consecutively admitted at the participating institutions' Emergency Department (ED) will be considered for enrolment. The primary outcome measure will be the need for orotracheal intubation for primary respiratory failure lasting at least 48 hours within 7 days after trauma. The secondary outcome measures related to analgesia are: the basal analgesia protocol received during the first 7 days from ED admission and the median cumulative dose of morphine-equivalents received as rescue therapy during the first 7 days after trauma. The secondary outcome measure related to the sonographic evolution of thoracic lesions is the global and regional LUS.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Blunt thoracic trauma with a documentable lesion (T-AIS ≥ 2)
- •Age ≥ 18 years
- •GCS > 8 at ED admission
- •Total body CT scan available performed within 6 hours from ED admission
排除标准
- •- Penetrating thoracic trauma
- •Age < 18 years
- •GCS <= 8 at ED admission
- •Patients already intubated at ED arrival
- •Do not intubate order, for any reason
- •Intubation for Urgent/Emergent surgery within 24 hours from hospital arrival
结局指标
主要结局
needing for oro-tracheal intubation within day 7th from admission
时间窗: 7 days
次要结局
未报告次要终点