Laser Therapy for Perioral Dermatitis
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Change in number of lesions on side of the subject's face receiving laser therapy
研究概览
简要总结
Perioral dermatitis is an inflammation of the skin around the mouth. The cause of perioral dermatitis is unknown. Current treatment methods include oral antibiotics and topical calcenurin inhibitors, both of which produce side effects and have been relatively ineffective in the treatment of perioral dermatitis. The investigators hope to assess the efficacy of laser therapy in treatment of perioral dermatitis by using laser therapy on one half of the patients face and having patients apply topical medication (clindamycin) to their face for 8 weeks. The side of their face that receives laser therapy will be randomized. The investigators will assess the efficacy of laser therapy by counting the number of lesions that patients have before and after laser therapy, comparing photos of patient's perioral dermatitis before and after treatment, and having patient's rate their satisfaction of the treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
盲法说明
The investigators will not remind the participant or other investigators which side of the face received laser therapy, however the investigators cannot completely "blind" either the participant or other investigators as they will be awake or performing the therapy, respectively.
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 18 years or older
- •perioral dermatitis for greater than 1 month
- •willing to return for follow-up visits 2 weeks, 4 weeks and 8 weeks following treatment.
排除标准
- •skin type V or VI (due to risk of hyperpigmentation)
- •breastfeeding
- •unable to understand English
- •mentally impaired
- •incarcerated
研究组 & 干预措施
Pulse laser therapy
Pulse laser therapy will be randomly applied to right side or left side of face in addition to Clindamycin
干预措施: Clindamycin (Drug)
Clindamycin
Clindamycin only applied to side of face that does not receive pulse laser therapy.
干预措施: Clindamycin (Drug)
结局指标
主要结局
Change in number of lesions on side of the subject's face receiving laser therapy
时间窗: 8 weeks
counting number of lesions on each side of the face
Change in number of lesions on side of the subject's face receiving clindamycin alone (NO laser therapy)
时间窗: 8 weeks
counting number of lesions on each side of the face
次要结局
- Patient opinion of side that improved more(8 weeks)
研究者
Erica Ghareeb
Assistant Professor
West Virginia University
