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临床试验/NCT06768333
NCT06768333已完成不适用

The Need for Speed: Comparing the Speed of Glucose Absorption During Repeated Sprint Cycling

Lancaster University2 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2025年1月6日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
10
试验地点
2
主要终点
Blood Glucose

研究概览

简要总结

The purpose of this study is to look at how fast commercially available supplements containing carbohydrates can get into the bloodstream during repeated sprint cycles. This will build from a pervious study where the investigators tested these supplements on healthy participants during a resting oral glucose tolerance trial. The investigators will be testing three supplements, namely Voom Pocket Rocket, SIS Go Isotonic Energy Gel, and Maurten Gel 160. Each participant will complete all three conditions, consuming one of each supplement at random per condition. The study requires participation from male and female runners, cyclists and triathletes who are aged between 18-40.

Each visit will take approximately 1 hour, and three experimental visits per participant. The study will involve frequent blood sampling and the continuous monitoring of gas exchange (oxygen/carbon dioxide). Blood sampling via cannulation will be used to analyse the lactate, glucose, and electrolyte content of the blood. Gas exchange will measure the oxygen breathed in and carbon dioxide breathed out throughout the exercise.

The investigators plan to carry out the study on 10 participants who will be a mix of male and female runners, cyclists and triathletes.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Double (Participant, Investigator)

盲法说明

Both the participants and investigators will be blinded to what supplement they are consuming on each visit. Each supplement will taste the same, and be placed into identical packaging, and be randomly labelled (e.g., A, B, C). This will be done to avoid potential bias.

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Aged between 18-40 years
  • Male or female
  • Tier 2 athletes - local level representation, training ~ 3 times per week, training with a purpose to compete, identify with a specific sport, limited skill development (McKay et al., 2021)

排除标准

  • Allergies to any listed ingredients on any supplements.
  • Diabetes (type 1 or 2)
  • Any medical conditions
  • Any injury that would prevent them from exercising
  • Anyone using drugs or medication (not including contraception)
  • Anyone consuming alcohol within 24 hours of the study
  • Exercise must be restricted within 24 hours of the study
  • Caffeine must not be consumed within 24 hours of testing as it can significantly enhance carbohydrate oxidation rates (Yeo et al., 2005)
  • Diets including high-carbohydrate-low-fat (HCLF), low-carbohydrate-high-fat (LCHF), ketogenic, and/or glycogen manipulation diets (Rauch et al., 2022)

结局指标

主要结局

Blood Glucose

时间窗: Blood glucose measures will be taken 35 minutes after consuming the supplement(s) (baseline), after the 3 minute warmup, and then after every 15 second sprint and every 3 minute period of active recovery

Frequent blood sampling for blood glucose (1ml after every stage of both sprint cycling and active recovery) followed by analysis in the Biosen Analyser

Blood Lactate

时间窗: Blood lactate measures will be taken 35 minutes after consuming the supplement(s) (baseline), after the 3 minute warmup, and then after every 15 second sprint and every 3 minute period of active recovery

Frequent blood sampling for blood lactate (1ml after every stage of both sprint cycling and active recovery) followed by analysis in the Biosen Analyser

Gas Exchange

时间窗: Gas exchange will be measured continuously throughout the 20 minutes of exercise, starting at the warmup

Gas exchange measured throughout each 20 minute exercise via a Cortex Metalyzer

次要结局

  • Blood electrolyte content(Blood electrolyte measures will be taken 35 minutes after consuming the supplement(s) (baseline), after the 3 minute warmup, and then after every 15 second sprint and every 3 minute period of active recovery)
  • Rate of Percieved exertion (RPE)(RPE will be measured at the end of the warmup and the end of the final sprint stage)
  • Gastrointestinal (GI) Discomfort Questionnaire(GI Discomfort will be measured 5 minutes before and 5 minutes after exercise)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dr. Chris Gaffney

Principal Investigator

Lancaster University

研究点 (2)

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