16-Week Yoga Improves Bone Density, Metabolism in Elderly Osteoporosis: A Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- bone mineral density
研究概览
简要总结
This study was designed to evaluate the impact of a 16-week yoga program on BMD, bone metabolism markers, and physical fitness in elderly patients with OP.
详细描述
To assess the effects of a 16-week yoga intervention on bone mineral density (BMD), bone metabolism, and physical fitness in elderly patients with osteoporosis. This randomized controlled trial enrolled 60 adults aged 50 years or older with clinically confirmed osteoporosis. Based on personal preference, participants were assigned to either a yoga group or a control group. The intervention consisted of supervised yoga sessions conducted twice weekly for 16 weeks. The yoga intervention included physical postures, breathing exercises, and meditation/relaxation techniques. Health outcomes were assessed at baseline, mid-intervention (8 weeks), and post-intervention (16 weeks). Primary outcomes included changes in BMD at the lumbar spine and hips. Secondary outcomes comprised serum levels of osteocalcin, procollagen type 1 N-terminal propeptide (P1NP), β-CTX, 25-hydroxyvitamin D, calcium, phosphate, and performance in physical function tests, including grip strength, chair stand, single-leg balance, and timed up-and-go. This randomized controlled trial aims to find out the effect of yoga intervention on bone mineral density (BMD), bone metabolism, and physical fitness in elderly patients with osteoporosis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age ≥50 years;
- •diagnosed with osteoporosis using dual-energy X-ray absorptiometry (DXA);
- •able to independently perform required assessments;
- •voluntary participation in yoga intervention.
排除标准
- •secondary osteoporosis;
- •severe cardiovascular, cerebrovascular, hepatic, or renal diseases;
- •cognitive impairment;
- •severe motor dysfunction;
- •regular participation in structured exercise programs, such as yoga or resistance training, within the past six months.
研究组 & 干预措施
experimental group
Participants in the yoga intervention group attended supervised yoga classes twice per week for 16 weeks. Each yoga session lasted approximately 60 minutes and was conducted by certified yoga instructors. Sessions comprised breathing exercises, structured yoga postures, and relaxation. Heart rate was monitored regularly during sessions to maintain appropriate intensity.
干预措施: Yoga (Behavioral)
control group
Participants in the control group were instructed to maintain their usual activities and not initiate any new structured exercise programs during the study period
结局指标
主要结局
bone mineral density
时间窗: baseline and 4 month
assessed by dual-energy X-ray absorptiometry (DXA, HOLOGIC Discovery Wi, Bedford, MA, USA), at lumbar spine and bilateral hips. Osteoporosis was diagnosed according to the World Health Organization criteria based on T-scores.
次要结局
- β-terminal telopeptide of I collagen (β-CTx)(baseline and 4 month)
- N-MID Osteocalcin(baseline and 4 month)
- Procollagen 1 N-terminal Propeptide(baseline and 4 month)
- 25-hydroxyvitamin D(baseline and 4 month)
- Lower Limb Major Muscle Group Strength (Quadriceps Femoris, HamstringsTriceps Surae, Tibialis Anterior, lliopsoas)(Baseline, 2 Months Post-ntervention, and 4 Months Post-Intervention)