A Comparative Study To Assess The Effectiveness 0.75% Ropivacaine With Dexmedetomidine Versus 0.75% Ropivacaine With Magnesium Sulphate In Ultrasound Guided Supraclavicular Brachial Plexus Block For Upperlimb Surgeries.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- Time of onset of sensory blockade.
研究概览
简要总结
Supraclavicular brachial plexus block is considered to be one of the most effective anaesthetic procedures for upperlimb surgeries .In this study we intend to compare the onset and duration of sensory and motor blockade obtained from the administration of 0.75% Ropivacaine with Dexmedetomidine and Magnesium sulphate as adjuvants for this block.The study is conducted in a private medical college setting in Kerala.For this study patients with distal upperlimb injuries , satisfying the inclusion criteria are randomly selected to two groups of 26 each using sealed envelope method. Then group A will be given 0.75% Ropivacaine with Dexmedetomidine and group B will be given Ropivacaine with Magnesium Sulphate.The onset of sensory block is defined as Hollman scale of 4 using pinprick.The onset of motor block is defined as achievement of Modified Bromage scale of 3.Duration of sensory block is defined as the time of block to the requirement of rescue analgesia.The duration of motor block is defined as the time of block to the arm raising above the head.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •patients undergoing upper limb surgeries under supraclavicular brachial plexus block.Aged between 18 to 65 years and are ASA classes 1 and 2 will be included in the study after obtaining informed consent.
排除标准
- •preexisting peripheral neuropathy .Bleeding disorders.Infection at injection site.Allergy to local anesthetics,magnesium sulphate.surgeries lasting more than 3 hours.Patients with history suggestive of arrythmias.patients who do not give consent.
结局指标
主要结局
Time of onset of sensory blockade.
时间窗: Time of onset of sensory blockade assessed at 0 minute,1 minute,3 minutes,5minutes,7minutes,9 minutes,10 minutes likewise every 2 minutes for 20 minutes | Time of onset of motor blockade assessed at 0 minute,1 minute,3 minutes,5 minutes,7 minutes likewise every 2 minutes for 20 minutes | Duration of sensory block assessed at 4 hours,8 hours, 12 hours,16 hours,20 hours,24 hours. | duration of motor block assessed at 4 hours, 8 hours,12 hours, 16 hours , 20 hours , 24 hours.
Time of onset of motor blockade.
时间窗: Time of onset of sensory blockade assessed at 0 minute,1 minute,3 minutes,5minutes,7minutes,9 minutes,10 minutes likewise every 2 minutes for 20 minutes | Time of onset of motor blockade assessed at 0 minute,1 minute,3 minutes,5 minutes,7 minutes likewise every 2 minutes for 20 minutes | Duration of sensory block assessed at 4 hours,8 hours, 12 hours,16 hours,20 hours,24 hours. | duration of motor block assessed at 4 hours, 8 hours,12 hours, 16 hours , 20 hours , 24 hours.
duration of motor block .
时间窗: Time of onset of sensory blockade assessed at 0 minute,1 minute,3 minutes,5minutes,7minutes,9 minutes,10 minutes likewise every 2 minutes for 20 minutes | Time of onset of motor blockade assessed at 0 minute,1 minute,3 minutes,5 minutes,7 minutes likewise every 2 minutes for 20 minutes | Duration of sensory block assessed at 4 hours,8 hours, 12 hours,16 hours,20 hours,24 hours. | duration of motor block assessed at 4 hours, 8 hours,12 hours, 16 hours , 20 hours , 24 hours.
Duration of sensory block.
时间窗: Time of onset of sensory blockade assessed at 0 minute,1 minute,3 minutes,5minutes,7minutes,9 minutes,10 minutes likewise every 2 minutes for 20 minutes | Time of onset of motor blockade assessed at 0 minute,1 minute,3 minutes,5 minutes,7 minutes likewise every 2 minutes for 20 minutes | Duration of sensory block assessed at 4 hours,8 hours, 12 hours,16 hours,20 hours,24 hours. | duration of motor block assessed at 4 hours, 8 hours,12 hours, 16 hours , 20 hours , 24 hours.
次要结局
- Hemodynamic stability(monitoring of systolic blood pressure, diastolic blood pressure ,heart rate & oxygen saturation done at o hours,1hour,2hours,3hours,4hours,8hours,12hours,16hours,20hours, 24 hours after administration of supraclavicular brachial plexus block)