白内障超声乳化术对 2 型糖尿病患者角膜内皮细胞的影响 Corneal Endothelial Cell Changes After Phacoemulsification in Patients With Type 2 Diabetes Mellitus
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 主要终点
- Comparison of the corneal endothelial cell density before-after cataract surgery
研究概览
简要总结
This study investigate the change of the corneal endothelial cells in patients with type 2 diabetes after phacoemulsification with intraocular lens implantation.
详细描述
The investigators do the clinical prospective study including 30 patients with type 2 diabetes and 30 control patients without diabetes scheduled to undergo cataract surgery. The corneal endothelial cell density, variation in endothelial cell size (CV), percentage of hexagonal cells, and central corneal thickness(CCT) were recorded at baseline and at 3 months postoperatively.Then, the investigators compared the two sets of data. At last observing the change of the corneal endothelial cells in patients with type 2 diabetes after phacoemulsification with intraocular lens implantation.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 58 Years 至 86 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •the experimental group:
- •Clinical diagnosis of cataract
- •Type 2 diabetes mellitus
- •The recent blood glucose control was stable
- •The glycosylated hemoglobin < 8%
- •The control group:
- •Clinical diagnosis of cataract
- •No history of type 2 diabetes
排除标准
- •Corneal lesions
- •Anterior inflammation
- •Ocular trauma or surgical history
- •Corneal endothelial cell density < 1500 / mm squared
结局指标
主要结局
Comparison of the corneal endothelial cell density before-after cataract surgery
时间窗: half year
Comparison of the corneal endothelial cell density before-after cataract surgery，the density is expressed in terms of the number of cells per square millimeter.
次要结局
- Comparison of the endothelial cell size before-after cataract surgery(half year)
- Comparison of the percentage of hexagonal cells before-after cataract surgery(half year)
- Comparison of the central corneal thickness(CCT) before-after cataract surgery(half year)