Severity Over Time of Early Forms of Spondyloarthritis, a Prospective Observational Study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 387
- 试验地点
- 1
- 主要终点
- spondyloarthritis severity
研究概览
简要总结
Spondyloarthritis (SpA) is a group of chronic inflammatory pathologies whose progression over time is poorly defined, and in particular the clinical and instrumental elements that can predispose to a condition of disease severity are not completely known. It would be important to have an idea of what the predisposing factors are, possibly already at baseline, and possibly also at follow up, of severe disease, so as to be able to act early with more aggressive and targeted therapies on these patients, so as to achieve remission.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age >18 years;
- •Diagnosis of SpA confirmed by the rheumatologist with duration of symptoms <
- •Signature of the written informed consent to the study
排除标准
- •Age < 18 years;
- •Patients suffering from other rheumatic pathologies (even in overlap), or genetic diseases such as Marfan syndrome, Ehlers Danlos syndrome
- •Any medical or psychiatric condition that in the judgment of the investigator would prevent the participant from complying with the protocol or completing the study according to the protocol.
- •Refusal to sign the informed consent to the study.
结局指标
主要结局
spondyloarthritis severity
时间窗: t0 baseline 3hours, t1 3 months 3hours,t2 6 months 3hours,t2 12months 3hours,every six months up to the tenth year
evaluation of disease severity at 10 years in the entire study population
次要结局
未报告次要终点