ISRCTN17987569已完成未知
Can patients with multiple breast cancers in the same breast avoid mastectomy by having multiple lumpectomies to achieve equivalent rates of local breast cancer recurrence? A randomised controlled feasibility study
niversity College London0 个研究点目标入组 50 人开始时间: 2018年4月20日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 50
研究概览
简要总结
2022 Interim results article in https://pubmed.ncbi.nlm.nih.gov/35227311/ Qualitative results (added 28/06/2022)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- Female
入选标准
- •1. Aged >40 years with MIBC
- •2. Minimum of two invasive foci of breast cancer
- •3. Suitable for Therapeutic Mammoplasty
- •4. Fit for adjuvant therapy
- •5. Willing and able to provide written informed consent
排除标准
- •1. Neo-adjuvant therapy ?
- •2. Women considered high risk by local centre or known to have BRCA1/2 gene mutation ?
- •3. Ductal Carcinoma in situ (DCIS) only, and extensive DCIS ?
- •4. Bilateral breast cancers ?
- •5. Previous breast cancer (invasive or DCIS in either breast) ?
- •6. Pregnancy as confirmed on blood tests or ultrasound examination.
- •7. Metastatic disease.
- •8. Any previous type of breast radiotherapy ?
- •9. Significant other clinical risk factors and co-morbidities at the discretion of the treating clinicians.
- •10. Previous or concomitant malignancy except adequately treated: non-melanomatous skin cancer; in situ carcinoma of the cervix and in situ melanoma
研究者
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