Posterolateral Corpectomy With Pyramesh Titanium Cage Reconstruction in Dorsolumber Metastatic Lesions
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 26
- 试验地点
- 2
- 主要终点
- (Quebec scale) to assess back pain in three years
研究概览
简要总结
The vertebral column represents the most common bony site for metastasis with an incidence ranged from 30% to 70% in patients with metastatic neoplasms. The dorsal spine carries the highest frequent site for metastasis all over the vertebral column followed by the lumber spine. These metastatic lesions are clinical entities that often necessitate a complex spinal decompression and anterior reconstruction. Posterolateral approaches alone allow for excellent decompression with transpedicular fixation and safe visualization of the neural elements for corpectomy and reconstruction so the investigators can avoid the complications that can be happened with the staged surgery.
Purpose: investigators' aim in the study is to report cases and evaluate investigators' approach for fixation and assess the postoperative period regarding pain improvement and neurological deficit.
详细描述
At neurosurgery department in Sohag faculty of medicine, Between August 2014 and August 2017, 26 patients with single dorsolumbar metastatic spinal lesions with vertebral body collapse underwent a single-stage, circumferential corpectomy and anterior spinal reconstruction with a pyramesh titanium cage via a midline, posterior and lateral approach. Investigators included in the study patients with retropulsed fragment inside the canal that causes spinal cord compression with neurological manifestation. Metastatic work up was done for cases. Exclusion criteria include patients with more than one spinal metastases or extra-spinal metastasis, patients with other comorbidities as cardiac ill patients, patients with chronic renal failure and patients who received radiotherapy or chemotherapy within one year before surgery. A preoperative neurological assessment, full laboratory investigations were done. Investigators used the Quebec scale to assess the patients' improvement regarding pain, and muscle power scale to evaluate the motor.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 33 Years 至 67 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients with retropulsed fragment inside the canal that causes spinal cord compression with neurological manifestation.
排除标准
- •patients with more than one spinal metastases or extra-spinal metastasis.
- •patients with other comorbidities as cardiac ill patients, patients with chronic renal failure.
- •patients who received radiotherapy or chemotherapy within one year before surgery.
研究组 & 干预措施
patients with metastatic spinal lesions
corpectomy
干预措施: Posterolateral corpectomy (Procedure)
结局指标
主要结局
(Quebec scale) to assess back pain in three years
时间窗: 3 years
(Quebec Scale) the lower scale the better is the pain
(muscle power grading scale) to evaluate motor power using in three years
时间窗: 3 years
(Muscle power grading) the higher the grade the better is the motor power
次要结局
未报告次要终点
研究者
ahmed salaheldin mohammed saro
Assistant professor of neurosurgery
Sohag University
