ITMCTR2000003502尚未招募4 期
Traditional Chinese medicine syndrome characteristics of chronic hepatitis B patients with renal function damage and bone mineral density reduction after antiviral treatment and improvement of bone mineral density in chronic hepatitis B patients treated with tenofovir alafenamide fumarate
Guangdong Provincial Hospital of Chinese Medicine0 个研究点开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional study
入排标准
- 年龄范围
- 18 至 65（—）
- 性别
- All
入选标准
- •(1) having a history of chronic hepatitis B.
- •(2) Nucleoside (acid) antiviral treatment >= 24 weeks.
- •(3) willing to cooperate with the study and sign the informed consent.
- •(1) having a history of chronic hepatitis B.
- •(2) Age: 18-65 years old.
- •(3) Nucleoside (acid) antiviral treatment >= 24 weeks.
- •(4) combined with bone mineral density decreased.
- •(5) willing to cooperate with the research and sign the informed consent.
排除标准
- •(1) With a definite history of chronic kidney disease or osteoporosis before antiviral therapy.
- •(2) In addition to antiviral drugs, receiving kidney damage drugs or glucocorticoids that can lead to osteoporosis.
- •(3) Pregnant or lactating women.
- •(1) With a definite history of chronic kidney disease or osteoporosis before antiviral therapy.
- •(2) In addition to antiviral drugs, receiving kidney damage drugs or glucocorticoids that can lead to osteoporosis.
- •(3) Co-infection with HAV, HCV, HDV, HEV or HIV.
- •(4) Combined with pituitary, parathyroid and other diseases that affect calcium and phosphorus metabolism,or receiving drugs affecting calcium and phosphorus metabolism.
- •(5) Combined with secondary liver disease caused by severe malnutrition, total parenteral nutrition, weight loss after bariatric surgery, drug, environmental or industrial toxicosis.
- •(6) Combined with cardiovascular, brain, kidney and other serious organic diseases and severe primary diseases of hematopoietic system.
- •(7) Patients with poor compliance and unable to adhere to treatment.
- •(8) combined with liver cancer or cancers of other organs.
- •(9) Pregnant or lactating women.
研究者
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