跳至主要内容
临床试验/NCT07583836
NCT07583836招募中不适用

COMPARISON OF DELAYED VERSUS EARLY SURGICAL DECOMPRESSION FOR TRAUMATIC SPINAL CORD INJURY

Fauji Foundation Hospital1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2025年8月30日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
100
试验地点
1

研究概览

简要总结

To compare the outcome of early versus delayed surgical decompression among patients presenting with traumatic spinal cord injury in a tertiary care hospital.

详细描述

Despite the increasing advocacy for early surgery, significant variability persists in clinical practice. This inconsistency stems from conflicting evidence in the literature, with some studies reporting substantial neurological benefits from early intervention, while others find no significant difference compared to delayed surgery. Similarly, in our institute, both early and delayed decompressions are in practice, whichever considered suitable by the experts. But no study has done to date that compare the outcome of both techniques. Given these gaps, there is a pressing need for a comprehensive evaluation of the existing evidence to determine the optimal timing of surgical intervention for acute traumatic SCI especially among our local population where past evidence is scarce. So, this study seeks to contribute to this critical discourse by systematically evaluating the impact of early versus delayed surgical decompression on clinical outcomes in our local population. The study would not only add evidence to the global and local data but would also help the surgeons to choose the better technique in future as the technique with better outcome would be preferred in future among all the local patients who will present to our hospital with acute SCI. Adopting the treatment strategy with better outcome would also help to reduce the overall morbidity associated with a cute SCI in our local population.

Finally objectives are , to compare the outcome of early versus delayed surgical decompression among patients presenting with traumatic spinal cord injury in a tertiary care hospital.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Patients presenting with spinal cord injury (both cervical and thoracic) as per described in the operational definition
  • Age from 18-60 years
  • Both male and female patients

排除标准

  • Patients with penetrating spinal injuries such as gunshot/stab wounds
  • Patients with pre-existing neurological conditions like myelopathy etc.
  • Patients with any kind of malignancy
  • Patients having CSF infection etc.
  • Patients who are not fit for general anesthesia (i.e. ASA Grade >2 Annexure-B)
  • Diagnosis of subclinical or clinical polyneuropathy
  • Non-traumatic or pathological fractures or cord compression
  • Inability to cooperate with preoperative physical examination because of cognitive impairment
  • Patients with previous spinal column or SCI.

研究者

发起方
Fauji Foundation Hospital
申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验