跳至主要内容
临床试验/NCT04091074
NCT04091074Unknown1 期

Safety and Effectiveness of Ticagrelor in Patients Undergoing Carotid Stenting

Assiut University0 个研究点目标入组 26 人开始时间: 2022年1月1日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
1 期
入组人数
26
主要终点
compare efficacy of ticagrelor and clopidogrel in patients undergoing carotid stenting

研究概览

简要总结

patients undergoing carotid stenting take dual anti platelet therapy to prevent thrombotic complications usually used drugs are aspirin plus clopidogrel but there are patients not respond so ticagrelor may be an effective and safe alternative

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Ischemis stroke of both sex.
  • More than 18 years.
  • Accepting all study requirements.

排除标准

  • Refuse to comply with all study requirements.
  • bleeding tendency or liver diseases

研究组 & 干预措施

aspirin + ticagrelor before carotid stenting

Active Comparator

patients undergoing carotid stenting take aspirin 150 mg + ticagrelor 90mg for 15 days before carotid stenting

干预措施: Ticagrelor (Drug)

aspirin + ticagrelor before carotid stenting

Active Comparator

patients undergoing carotid stenting take aspirin 150 mg + ticagrelor 90mg for 15 days before carotid stenting

干预措施: Carotid stenting (Procedure)

aspirin + clopidogrel before carotid stenting

Active Comparator

patients undergoing carotid stenting take aspirin 150 mg + clopidogrel 75 mg for 15 days before carotid stenting

干预措施: Clopidogrel (Drug)

aspirin + clopidogrel before carotid stenting

Active Comparator

patients undergoing carotid stenting take aspirin 150 mg + clopidogrel 75 mg for 15 days before carotid stenting

干预措施: Carotid stenting (Procedure)

结局指标

主要结局

compare efficacy of ticagrelor and clopidogrel in patients undergoing carotid stenting

时间窗: 15 days before carotid stenting

patients undergoing carotid stenting are divided into 2 groups comparing efficacy of ticagrelor and clopidogrel

Compare safety of ticagrelor and clopidogrel in patients undergoing carotid stenting

时间窗: 15 days before carotid stenting

Patients undergoing carotid stenting are divided into two groups comparing safety of ticagrelor and clopidogrel

次要结局

  • Pattern of carotid stenosis(1 year)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Osama Ibrahim Aboelfath Ibrahim

Osama Ibrahim Aboelfath Ibrahim

Assiut University

相似试验

已完成
2 期
Efficacy and Safety of Low-dose TicagrelorCoronary Artery Disease
NCT03381742First Affiliated Hospital of Harbin Medical University3,043
已完成
3 期
Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic StrokeIschemic Stroke, Acute
NCT06316570Beijing Tiantan Hospital1,382
进行中(未招募)
1 期
Comparing a combination therapy of Brilique and Trombyl against Trombyl as single therapy after bypass surgery in patients with myocardial infarction or instable angina.Coronary artery multi-vessel disease and left main stenosisMedDRA version: 20.0 Level: LLT Classification code 10011098 Term: Coronary bypass System Organ Class: 100000004865
EUCTR2017-001499-43-DKSahlgrenska University Hospital2,200
进行中(未招募)
1 期
Comparing a combination therapy of Brilique and Trombyl against Trombyl as single therapy after bypass surgery in patients with myocardial infarction or instable angina.Coronary artery multi-vessel disease and left main stenosisMedDRA version: 20.0Level: LLTClassification code 10011098Term: Coronary bypassSystem Organ Class: 100000004865
EUCTR2017-001499-43-SESahlgrenska University Hospital2,200
招募中
1 期
Comparing a combination therapy of Brilique and Trombyl against Trombyl as single therapy after bypass surgery in patients with myocardial infarction or instable angina.Coronary artery multi-vessel disease and left main stenosisMedDRA version: 20.0Level: LLTClassification code 10011098Term: Coronary bypassSystem Organ Class: 10042613 - Surgical and medical procedures
EUCTR2017-001499-43-ISSahlgrenska University Hospital2,200