Retrospective Study to Identify Risk Factors for Atrial Fibrillation After Ablation of Atrial Flutter by Radiofrequency of the Cavotricuspid Isthmus.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Cardiac surgery antecedents
研究概览
简要总结
Atrial flutter is a common condition that is effectively treated by ablation using radiofrequency. Due to its feasibility, effectiveness and low procedural risk, radiofrequency ablation is a first-line treatment of atrial flutter.
Several studies have been published concerning the factors associated with the occurrence of atrial fibrillation during or after flutter ablation, in patients with and without clinical history of atrial fibrillation. 26 to 46% of patients are likely to develop it, according to ECG or Holter diagnoses. The figure rises to more than 50% with a diagnosis with an implantable loop recorder.
In patients without a prior history of atrial fibrillation before ablation, anticoagulants are routinely administered 4-6 weeks after flutter removal by most cardiologists.
Although there are no specific guidelines for anticoagulation after flutter ablation, it is currently recommended to treat the patient as for atrial fibrillation. It is therefore crucial to identify in advance patients at high risk of atrial fibrillation after flutter ablation, in order to assess the appropriateness of maintaining oral anticoagulant therapy.
The objectives of this study are:
- to evaluate the frequency and identify the factors predicting the occurrence of atrial fibrillation after flutter ablation
- to determine the risk of a stroke occurring in patients with atrial fibrillation after flutter ablation.
The database consists in patients of the CHU Brugmann Hospital treated between 1996 and 2018.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients treated at the CHU Brugmann Hospital for flutter ablation by radiofrequency between 1996 and 2018.
排除标准
- 未提供
结局指标
主要结局
Cardiac surgery antecedents
时间窗: One day
Presence of cardiac surgery antecedents at the date of flutter ablation
Age at ablation
时间窗: One day
Age of the patient at the date of the flutter ablation
Gender
时间窗: One day
Gender of the patient at the date of the flutter ablation
Antecedents of ischemic cardiomyopathy
时间窗: One day
Antecedents of ischemic cardiomyopathy (yes/no) at the date of flutter ablation
Antecedents of dilated cardiomyopathy
时间窗: One day
Antecedents of dilated cardiomyopathy (yes/no) at the date of flutter ablation
Chronic pulmonal disease
时间窗: One day
Chronic pulmonal disease diagnosed at the date of flutter ablation
Stroke after flutter ablation
时间窗: One year
Occurence of stroke after the flutter ablation
Diabetes
时间窗: One day
Diabetes diagnosis (yes/no) at the date of flutter ablation
Arterial hypertension
时间窗: One day
Presence of arterial hypertension on the day of flutter ablation
Antecedents of stroke
时间窗: One day
Antecedents of stroke
Antecedents of peripheric thromboembolic events
时间窗: One day
Antecedents of thromboembolic events on the day of flutter ablation
Antecedents of cardiomyopathy
时间窗: One day
Antecedents of cardiomyopathy (yes/no) at the date of flutter ablation
Atrial fibrillation antecedents
时间窗: One day
Antecedents of Atrial fibrillation at the date of flutter ablation
Peripheric thromboembolic events after flutter ablation
时间窗: One year
Thromboembolic events after flutter ablation
Left ventricular ejection fraction of the heart
时间窗: One day
Left ventricular ejection fraction of the heart at the day of flutter removal (echographic data)
Beta-blockers post-ablation
时间窗: One day
Prescription of Beta-Blockers after the flutter ablation (yes/no)
Amiodarone post-ablation
时间窗: One year
Prescription of amiodarone after the flutter ablation (yes/no)
Left atrium size of the heart
时间窗: One day
Left atrium size of the heart at the day of flutter removal (echographic data)
Class I antiarrhythmic drugs post-ablation
时间窗: One year
Prescription of Class I antiarrhythmic drugs post-ablation
Pulmonary arterial pressure
时间窗: One day
Pulmonary arterial pressure at the day of flutter removal (echographic data)
Atrial Fibrillation apparition delay
时间窗: Up to one year
Delay of apparition of atrial fibrillation after flutter removal
次要结局
未报告次要终点
研究者
José Castro
Head of cardiology clinic
Brugmann University Hospital