Relation between chronic endometritis and recurrent miscarriage

Department of Obstetrics and Gynecology, Ahmadi hospital, Kuwait.0 个研究点目标入组 110 人开始时间: 2018年4月13日最近更新: 2022年11月14日

试验速览

阶段: 未知
状态: 已完成
发起方
入组人数: 110

研究概览研究设计入排标准研究者记录与标识符相似试验

研究概览

简要总结

Summary of results: The prevalence of chronic endometritis in women with recurrent miscarriage was 31.8% using chronic endometritis-related hysteroscopic signs, while it was 38.2% using immunohistochemical staining and endometrial cultures (p = 0.4). Chronic endometritis-related hysteroscopic signs had 64.1% sensitivity, 85.9% specificity, 71.4% positive predictive value (PPV), 81.3% negative predictive value (NPV), and 78.2% overall accuracy in diagnosing chronic endometritis. Most cases of chronic endometritis (> 81%) were caused by Mycoplasma and common pathogens.

研究设计

研究类型: Interventional
分配方式: Non-randomised trial
主要目的: Diagnosis

入排标准

年龄范围: 20 Years 至 40 Years（—）
性别: Female

入选标准

•Patients and methods: Analysis of the hospital records over the last 5 years from January 2012 to January 2017 to identify women with unexplained recurrent miscarriage, after approval of the Obstetrics and Gynecology department.
•Inclusion criteria includes; women who will give consent, >20-40 years, with 3 or more miscarriages before 22 weeks’ gestation.

排除标准

•Exclusion criteria includes; family history of RM, uterine abnormalities, hormonal or metabolic disorders, severe male factor infertility, previous surgery for myoma and/or endometriosis, clinical or ultrasound diagnosis of endometriosis, known clinical autoimmune disease, anti-phospholipid syndrome (APS), thrombophilic condition requiring anticoagulant therapy, and unwilling to give informed consent.

研究者

发起方

Department of Obstetrics and Gynecology, Ahmadi hospital, Kuwait.

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