NCT06509295尚未招募不适用
Effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Postoperative Pain and Bacterial Reduction in Mandibular Premolars With Necrotic Pulps. A Randomized Clinical Trial.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 30
- 主要终点
- Effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Postoperative Pain in Mandibular Premolars with Necrotic Pulps.
研究概览
简要总结
This study aims to assess the effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Postoperative Pain and Bacterial Reduction in Mandibular Premolars with Necrotic Pulps.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Systematically healthy patient (ASA I, II).
- •Age between 20 and 55 years
- •Male or female.
- •Mandibular premolar teeth having single canals diagnosed with pulp necrosis with asymptomatic apical periodontitis.
- •Radiographic examination using Digora intraoral periapical sensor plate and software showing mandibular premolars with (0-2 mm) periapical radiolucency.
排除标准
- •Medically compromised patients having significant systemic disorders. (ASA III or IV).
- •History of intolerance to NSAIDS.
- •Teeth with:
- •Immature roots
- •Vital pulp tissues.
- •Association with swelling.
- •Acute peri-apical abscess or acute exacerbation of a chronic abscess.
- •Mobility Grade II or III.
- •Previously accessed or endodontically treated
- •Deep periodontal pockets more than 4 mm
- •Vertical root fractures, coronal perforation, calcification, and external or internal root resorptions.
- •Patients who could not interpret the NRS.
- •Patients with diabetes, immune-compromising, and immunosuppression disease and pregnant women were, also, excluded.
结局指标
主要结局
Effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Postoperative Pain in Mandibular Premolars with Necrotic Pulps.
时间窗: measured at 6, 12, 24, 48 hours after single visit treatment
measuring tool: Numerical Rating Scale (NRS). Unite of measurement: Categorical None 0 Mild 1-3 Moderate 4-6 Severe 7-10 Time of measurements: At 6, 12, 24, 48- hours post-treatment.
次要结局
- Effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Bacterial Reduction in Mandibular Premolars with Necrotic Pulps.(T0=Baseline immediate after access preparation . T1=Post-instrumentation. T1(within an hour))
- Number of analgesic tablets taken by the patient after endodontic treatment(Up to 48 hours postoperative.)
研究者
Youmna Yassen
Principle investigator, resident at faculty of dentistry
Cairo University
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