NCT04935138终止不适用
Cell-free DNA Analysis of Chromosome Anomalies in Early Pregnancy Loss
Quest Diagnostics-Nichols Insitute1 个研究点 分布在 1 个国家目标入组 78 人开始时间: 2021年6月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 78
- 试验地点
- 1
- 主要终点
- microarray analysis of products of conception (POC)
研究概览
简要总结
The study assesses the accuracy of cell-free DNA (cfDNA) analysis in detecting whole chromosomal aneuploidies from maternal plasma of patients with early, missed miscarriage.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •5-20 weeks of gestation by ultrasound
- •Miscarriage diagnosed by ultrasound
- •Pregnancy tissue still present in utero, including an empty sac, and not completely expelled
排除标准
- •Maternal age < 18 years
- •No visible pregnancy tissue on ultrasound
- •Multiple fetal gestation (> than singleton)
- •Pregnancy was conceived using in vitro fertilization (IVF) with preimplantation genetic testing for aneuploidy (PGT-A) performed on the transferred embryo
- •No microarray testing is planned on the product of conception
- •Previous normal non-invasive prenatal testing (NIPT) or diagnostic testing (chorionic villous sampling or amniocentesis) in the current pregnancy
- •Patient unable to provide consent
结局指标
主要结局
microarray analysis of products of conception (POC)
时间窗: 7 days
chromosome anomalies
次要结局
未报告次要终点
研究者
研究点 (1)
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