Patterns of care and survival of renal tumours in children in India-A retrospective multi-centric study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- 1.To describe the 5-year EFS and OS of children 18 year with renal tumours in India and factors associated with survival
研究概览
简要总结
Wilms tumour is 2ndmost common extracranial solid tumour and has excellent outcomes with combinedmodality of treatment. Two treatment approaches are being used worldwide. TheChildren’s Oncology Group (COG) in North America does upfront surgery in mostpatients. The approach of the SIOP Renal tumour Study group is to givepreoperative chemotherapy. In high income countries, survival of bothstrategies is the same.
In India there is apaucity of data on outcomes with different centres following differentprotocols. Hence this study has been planned to retrospectively analyse theepidemiology, clinical presentation, patterns of care and outcomes of childrenwith Wilms tumour in India. This information will set the baseline in India andguide future studies.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 0.00 Day(s) 至 18.00 Year(s)（—）
- 性别
- All
入选标准
- •â€¢All children less than 18 years of age diagnosed with primary renal tumour.
- •â€¢Patient who received partial treatment in the participating centre would still be eligible as long as adequate details of treatment done outside participating centre is available and follow-up was done.
排除标准
- •â€¢Relapsed cases •Patient where entire treatment details are not available.
结局指标
主要结局
1.To describe the 5-year EFS and OS of children 18 year with renal tumours in India and factors associated with survival
时间窗: 1.To describe the 5-year EFS and OS of children 18 year with renal tumours in India and factors associated with survival
次要结局
- 1.To describe the patterns of care of children 18 year with WT in India(2.To identify patterns of failure including mortality, progression/relapse and abandonment of treatment in children 18 year with WT in India)