NCT00600678已完成不适用
Characterisation of Gastric Emptying of a High Caloric Sip Feed Using the Paracetamol Absorption Method: Intraindividual Comparison of Paracetamol Pharmacokinetics After Oral co-Administration With Sip-Feed and After Intravenous Administration in Healthy Volunteers of Both Genders in an Open, Single Centre Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- - Gastric emptying after a single oral administration of a nutritional supplement
研究概览
简要总结
Measurement of gastric emptying time of an oral nutritional supplement (ProvideXtra DRINK) by using the paracetamol absorption method in healthy volunteers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •caucasian origin
- •BMI: 22kg/m2 - 27kg/m2;
排除标准
- •existing diseases and/or pathological findings, which might interfere with the safety, tolerability, absorption and/or pharmacokinetics of paracetamol (e.g. gastrointestinal or liver disease),
- •known allergic reactions to investigational products,
- •diseases and/or pathological findings, which could affect absorption, metabolism and/or gastric emptying (e.g. dyspepsia and gastroesophageal reflux),
- •regular medication which can influence hepatic biotransformation and/or absorption,
- •alcohol dependence, blood donation;
结局指标
主要结局
- Gastric emptying after a single oral administration of a nutritional supplement
时间窗: Time frame gastric emptying: blood samples will be taken at predefined time points, up to 12h after application of test product.
次要结局
- safety and tolerability(entire study)
研究者
研究点 (2)
Loading locations...
相似试验
招募中
不适用
Reaching a Caloric Goal Using a Gastric Sonar Versus Aspiration of Gastric Contents in Critically Ill Patients Receiving Nasogastric Enteral NutritionEnteral Nutrition Intolerance in Critically Ill PatientsNCT06557629Meir Medical Center50
已完成
不适用
The assessment of gastric emptying times of protein beverage in healthy volunteers: a randomized double-blind, crossover studypreoperative patientsJPRN-UMIN000020667Tohoku Kosai Hospital26
已完成
不适用
Gastric emptying after ingestion of clear fluids and nutritional liquidAspiration pneumoniaOral and Gastrointestinal - Normal oral and gastrointestinal development and functionRespiratory - Other respiratory disorders / diseasesInfection - Other infectious diseasesACTRN12614001106628Department of Anaesthesia and Pain Medicine at Royal Perth Hospital20
招募中
不适用
The clinical value of measuring gastric emptying in children with a severe generalized cerebral palsyDelayed gastric emptying10003018NL-OMON30780Erasmus MC, Universitair Medisch Centrum Rotterdam50
招募中
不适用
Determination of the gastric emptying time after consumption of standardized tube feeding in newborns, infants and children by sonographic measurement of the gastric antrumChildren aged 0-18 years are examined who are fed permanently or temporarily via an existing gastrostoma, PEG or nasal / oral gastric tube, regardless of the underlying disease.DRKS00023466Abteilung Anästhesie, Kinderintensiv- und Notfallmedizin, Kinder- und Jugendkrankenhaus Auf der Bult40