The Precondition of Retinopathy of Prematurity on Visual Acuity, Refraction, Biometric Values, Retinal and Choroidal Thickness in School-Aged Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 211
- 试验地点
- 1
- 主要终点
- Anterior Chamber Depth
研究概览
简要总结
Ophthalmological differences in school-aged children with and without a history of retinopathy of prematurity
详细描述
Aims: To compare functional (visual acuity and refractive error) and anatomical (biometric values, foveal and choroidal thickness) ophthalmological differences in school-aged children with and without a history of retinopathy of prematurity (ROP).
Settings and Design: Prospective Cross-Sectional Study
Methods and Material: The study was conducted prospectively in the ophthalmology department of Ankara Bilkent City Hospital. Subjects were divided into three groups: 29 children who were treated with laser photocoagulation (ROP-TxGroup), 26 children who developed ROP and did not need treatment (ROP-non-TxGroup), and 25 children who did not develop ROP (Premature Group). The 27 healthy children with a history of full-term born (Control Group), who were in a similar age group for 'control eye examination', were accepted as the control group. A total of 107 patients and 211 eyes were included in the study. Non-cycloplegic and cycloplegic refraction, best corrected visual acuity (BCVA), keratometry, axial length (AL) and anterior chamber depth (ACD), optical coherence tomography (OCT) macular and OCT subfoveal choroidal measurements were performed in all cases.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 5 Years 至 13 Years(Child)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Children with a history of ROP
排除标准
- •Stage 4-5 ROP, Presence of media opacities (such as cataract) Ocular trauma or ocular surgery Hydrocephalus or grade 3 and above intracerebral hemorrhage, Uncooperative children
结局指标
主要结局
Anterior Chamber Depth
时间窗: 4mounth after the procedure
Milimeter
K1 Flat and K2 Steep
时间窗: 4mounth after the procedure
Dioptre
Axial Length
时间窗: 4mounth after the procedure
Milimeter
Astigmatism
时间窗: 4mounth after the procedure
Dioptre
Best Corrected Visual Acuity
时间窗: 4mounth after the procedure
logMAR
Spherical Equivalents
时间窗: 4mounth after the procedure
Dioptre
Macular and Choroidal Thickness
时间窗: 4mounth after the procedure
Micrometer
次要结局
未报告次要终点
研究者
Ali Kutay KILINÇ
Principal Investigator
Ankara City Hospital Bilkent
