NCT06231524招募中不适用
Development and Validation of a AI Prognostic Model Based on DNA Ploidy, Stroma, and Nucleotyping for Synchronous Peritoneal Metastasis From Colorectal Cancer
Sixth Affiliated Hospital, Sun Yat-sen University1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2024年2月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Overall survival
研究概览
简要总结
Heterogeneity concerning survival in synchronous peritoneal metastasis from patients with colorectal cancer exists, thereby further classification is urgently required. This study aimed to validate a PSN-AI model based on DNA ploidy, stroma-tumor fraction, and nucleotyping (PSN) for the prediction of survival of synchronous peritoneal metastasis from colorectal cancer.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Histological proof of synchronous peritoneal metastases of a nonappendiceal colorectal adenocarcinoma.
- •Resectable disease determined by computed tomography (CT) and a peritoneal cancer index (PCI) of ≤20 at diagnostic laparoscopy or laparotomy;
- •No evidence of systemic (e.g. liver, lung) colorectal metastases within three months prior to enrolment;
- •Undergoing cytoreduction surgery for synchronous peritoneal metastasis from colorectal cancer.
排除标准
- •Combined with other types of malignant tumors.
结局指标
主要结局
Overall survival
时间窗: At least 1-year follow up
The time between the date of diagnosis and the date of death (due to any cause) or the date of last follow-up.
次要结局
- Progression-free survival(At least 1-year follow up)
研究者
研究点 (1)
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