A New 3D Virtual Reality-based Upper Limb Training to Improve Dexterity in Parkinson's Disease: a Randomized Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- fine finger movements
研究概览
简要总结
We investigate the impact of a 4-week virtual reality-based upper limb training in Parkinson's disease. The benefits on dexterity of this training program will be evaluated.
For these purposes, a randomised, two arm, single assessor blind, parallel design with a monocentric, study setup will be performed.
详细描述
Patients with Parkinson's disease (PD) suffer from significantly decreased coordination and have difficulties with precise hand/finger movements during the performance of both basic activities of daily living (ADL), such as dressing, grooming as well as higher ADL, such as cooking, shopping and regular medication intake. These difficulties further add to the burden of the disease, leading to reduced quality of life (QoL). A relatively new, but rapidly growing aspect of training in PD neurorehabilitation offers virtual reality (VR). We explore the effects of a VR-based upper limb hand training compared to a VR control training, which is less specific for dexterity. Moreover, we examine the effetcs of the trainings on upper limb related ADL, and therefore the impact on QoL in patients with PD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
VR upper limb hand training or VR control training
入排标准
- 年龄范围
- 40 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with confirmed PD, according to UK Brain bank Criteria
- •Hoehn & Yahr Stadium I to IV
- •Age 40 to 99 years
- •written and signed informed consent
- •self-reported dexterous difficulties
排除标准
- •MoCA <21/30
- •psychiatric disease
- •participation on other interventional trials
- •Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc.
- •severe visual impairment
结局指标
主要结局
fine finger movements
时间窗: 4 weeks
Coin rotation task (CRT): The CRT measures fine coordinated finger movements and is a suitable and valid dexterity test in patients with PD. The seconds for 20 halfturns will be measured.
次要结局
- self-reported dexterity related problems in daily living(4 weeks)
- self-reported problems in quality of life(4 weeks)
- motor function(4 weeks)
- hand dexterity(4 weeks)
- grip strenght(4 weeks)