Addressing Tetrachloroethylene Exposure in an Impacted Community: Residents' Concerns, Neurotoxic Effects, and Exposure Reduction
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 510
- 试验地点
- 2
- 主要终点
- Change in concerns about environmental chemical contamination in Martinsville.
研究概览
简要总结
Groundwater in Martinsville, IN, is contaminated by volatile organic compounds (VOCs), tetrachloroethylene (PCE) and trichloroethylene (TCE). Indoor air in some residential and commercial buildings is also contaminated with PCE and TCE. This study is being conducted to better understand the impact of low-level exposures to these compounds on community members' health. Data collected in this study will be used to help the community identify a course of action.
详细描述
Martinsville, IN, is a community of 11,000 people that overlays four groundwater contamination sites, including a U.S. Environmental Protection Agency (EPA)-designated Superfund site. The total area of groundwater contamination is over 60 acres and lies within a single aquifer. The contaminates are chlorinated volatile organic compounds (VOCs), primarily tetrachloroethylene (PCE) and trichloroethylene (TCE). These contaminants are thought to originate from several dry cleaning and metal degreasing operations. An activated carbon filtration system has been in operation since 2005 to remove PCE and chlorinated VOCs from the municipal water, which now meets EPA drinking water standards. However, a recent report from the Agency for Toxic Substances and Disease Registry concludes that people's health may be harmed by breathing indoor air contaminated via vapor intrusion, the migration of volatile compounds from contaminated groundwater and soil into buildings above. The long-term goal of this research is to understand how PCE exposure in communities affects health and to empower community members' participation in environmental health decision-making. In this project researchers will work with the community of Martinsville, IN to:
- Determine the extent and exposure levels to the contaminants by measuring the contamination in residents and at their homes.
- Assess the community's concern and perceptions about the contamination and associated health risks.
- Study the impact of the contaminants on visual and neurocognitive functions.
- Compare cancer rates in Martinsville to county and state rates.
The above information will help researchers and community partners co-design a targeted educational campaign to reduce community members' exposure to the contaminants.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Residents of Martinsville, Indiana
- •18 years or older
排除标准
- 未提供
结局指标
主要结局
Change in concerns about environmental chemical contamination in Martinsville.
时间窗: For Measure 1a, Time frame is from year 1 to year 3; for Measure 1b, Time frame is from year 1 to year 5.
This measure is based on the differences between the percentage of "Yes" responses to a close-ended, not scaled question at 3 different time points, administered via repeated surveys to the same sample of respondents. Are participants concerned about environmental chemical contamination in Martinsville? Yes / Somewhat / No / Refuse 1a. Changes in concerns about environmental chemical contamination in Martinsville from Year 1 to Year 3. This is based on the differences in percentage of yes responses to this question in surveys administered in Year 1 (Main survey, baseline) and Year 3 (online survey administered at the beginning of Year 3). 1b. Changes in concerns about environmental chemical contamination in Martinsville from Year 1 to Year 5. This is based on the differences in percentage of yes responses to this question in surveys administered in Year 1 (Main survey, baseline) and Year 5 (Online survey, post intervention).
Changes in awareness of possible exposure to chemicals from soil or groundwater in Martinsville.
时间窗: For Measure 2a, Time frame is from year 1 to year 3; for Measure 2b, Time frame is from year 1 to year 5.
This measure is based on the differences between the percentage of "Yes" responses to a close-ended, not scaled question at 3 different time points, administered via repeated surveys to the same sample of respondents. Are participants aware of possible exposure to chemicals from soil or groundwater in Martinsville? Yes / No / Refuse 2a. Changes in awareness of possible exposure to chemicals from soil or groundwater in Martinsville from Year 1 to Year 3. This is based on the differences in percentage of yes responses to this question in surveys administered in Year 1 (Main survey, baseline) and Year 3 (Online survey administered at the beginning of Year 3). 2b. Changes in awareness of available resources for exposure reduction from Year 1 to Year 5. This is based on the differences in surveys administered in Year 1 (Main survey, baseline) and Year 5 (Online survey, post intervention)
Change in willingness to have respondent's homes tested for chemical contamination from contaminated soil or groundwater.
时间窗: For Measure 3a, Time frame is from year 1 to year 3; for Measure 3b, Time frame is from year 1 to year 5.
This measure is based on the difference between the percentage of "Yes" responses to a close-ended, not scaled question at 3 different time points, administered via repeated surveys to the same sample of respondents. Are participants willing to have their home tested for chemical contamination from contaminated soil or groundwater? Yes / No / Refuse / Don't know 3a. Changes in willingness to have respondents' homes tested for the chemical contamination from Year 1 to Year 3. This is based on the differences in percentage of yes responses to this question in surveys administered in Year 1 (Main survey, baseline) and Year 3 (Online survey at the beginning of Year 3) 3b. Changes in willingness to have respondents' homes tested for the chemical contamination from Year 1 to Year 5. This is based on the differences in differences in percentage of yes responses to this question in surveys administered in Year 1 (Main survey, baseline) and Year 5 (Online survey, post intervention)
次要结局
未报告次要终点