Mucopolysaccharidosis Type II in Brazil: A Retrospective Secondary Database Study (Informatics Department of Brazilian Health System - DATASUS)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- Number of Participants with Comorbidities Associated with MPS II
研究概览
简要总结
The main aims of the study are to learn about the percentage of mucopolysaccharidosis type II (MPS II) in adults in Brazil as well as about the diagnosis process. No study medicines will be provided to participants in this study. The data available for participants diagnosed with MPS II in DATASUS (a database of the Informatics Department of Brazilian Health System) will be reviewed. No clinic visits will be required as part of participation in this study.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All MPS II cases of (International Classification of Diseases, 10th revision [ICD-10] E76.1) at any age reported in DATASUS from January 1st, 2008 to September 30th, 2020 will be included.
排除标准
- •MPS II cases reported outside this period will be excluded.
结局指标
主要结局
Number of Participants with Comorbidities Associated with MPS II
时间窗: From January 1, 2008 to September 30, 2020
Comorbidities will be like respiratory infections, carpal tunnel syndrome and hernia. Number of participants with comorbidities associated with MPSII will be reported based on the retrospective data of participants collected from the database (DATASUS).
Number of Participants Diagnosed With MPS II
时间窗: From January 1, 2008 to September 30, 2020
Number of participants diagnosed with MPS II will be reported based on the retrospective data of participants collected from the database (DATASUS).
Age of MPS II Diagnosis
时间窗: From January 1, 2008 to September 30, 2020
Age of MPS II diagnosis will be calculated from the date of birth and date of diagnosis. Retrospective data of participants will be collected from the database (DATASUS).
次要结局
- Number of Health Care Professionals Consulted(From January 1, 2008 to September 30, 2020)
- Number of Health Care Professionals Who Diagnosed MPS II(From January 1, 2008 to September 30, 2020)
- Number of Treatments Received Before and After MPS II Diagnosis(From January 1, 2008 to September 30, 2020)
- Time to MPS II Diagnoses(From January 1, 2008 to September 30, 2020)
- Time Between MPS Diagnosis II and Start of Treatment(From January 1, 2008 to September 30, 2020)