Tsui Test as a Predictor of Bupivacaine Consumption in Labour Epidurals
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 102
- 试验地点
- 2
- 主要终点
- Consumption of bupivacaine in mg/hour in the first 2 hours of epidural anesthesia
研究概览
简要总结
Low current electrical stimulation test, also called the Tsui test, has been used successfully to confirm the catheter location in the epidural space in various patient populations. The results of this study will show whether or not doing a Tsui test can predict inadequate epidural analgesia early in the course of placing the epidural, so that the appropriate measures could be applied immediately upon gathering unfavorable results.
详细描述
Despite its very high success rate, the epidural technique remains a rather blind technique, and failures continue to occur. The incidence and reasons for failure are not well understood. The Tsui test is not routinely performed with each epidural catheter insertion, but rather it is used when there is suspicion about the catheter location.
In this study, the Tsui test will be performed twice during the epidural procedure, and bupivacaine consumption will be recorded for the first 2 hours.
Information gained from this study could have great impact in clinical practice, since the incidence of inadequate labor analgesia is still relatively high (10-20%), leading to maternal distress and disappointing labor experience.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Women over 18 years of age requesting an epidural for labor and delivery
- •Cervix dilated 0-5 cm and pain VAS>6
- •Able to communicate in English
- •Informed consent
排除标准
- •Refusal to provide written informed consent
- •Patients unable to communicate in English
- •Contraindication to regional anesthesia
- •Allergy or hypersensitivity to lidocaine, bupivacaine or fentanyl
- •Sedatives or opioids received prior to insertion of epidural catheter
- •Abnormal vertebral anatomy, such as previous spine surgery and scoliosis
- •Coexisting neurological disorders
- •Patients with implanted electronic devices
结局指标
主要结局
Consumption of bupivacaine in mg/hour in the first 2 hours of epidural anesthesia
时间窗: 2 hours
次要结局
- Incidence of inadequate epidural block.(2 hours)
- Current (mA) needed to elicit motor response; 1. before test dose and 2. 5 minutes after test dose.(5 minutes)
- Contraction pattern elicited by the Tsui test at baseline and after test dose.(5 minutes)